CI/CD

Comprehensive toolkit for survival analysis and time-to-event modeling in Python using scikit-survival. Use this skill when working with censored survival data, performing time-to-event analysis, fitting Cox models, Random Survival Forests, Gradient Boosting models, or Survival SVMs, evaluating survival predictions with concordance index or Brier score, handling competing risks, or implementing any survival analysis workflow with the scikit-survival library.

Access European Nucleotide Archive via API/FTP. Retrieve DNA/RNA sequences, raw reads (FASTQ), genome assemblies by accession, for genomics and bioinformatics pipelines. Supports multiple formats.

Deep generative models for single-cell omics. Use when you need probabilistic batch correction (scVI), transfer learning, differential expression with uncertainty, or multi-modal integration (TOTALVI, MultiVI). Best for advanced modeling, batch effects, multimodal data. For standard analysis pipelines use scanpy.

Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target identification.

This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.

Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. This skill should be used when analyzing any scientific data file to understand its structure, content, quality, and characteristics. Automatically detects file type and generates detailed markdown reports with format-specific analysis, quality metrics, and downstream analysis recommendations. Covers chemistry, bioinformatics, microscopy, spectroscopy, proteomics, metabolomics, and general scientific data formats.

Vendor-agnostic lab automation framework. Use when controlling multiple equipment types (Hamilton, Tecan, Opentrons, plate readers, pumps) or needing unified programming across different vendors. Best for complex workflows, multi-vendor setups, simulation. For Opentrons-only protocols with official API, opentrons-integration may be simpler.

Use this skill when stuck in circular debugging, when solutions aren't working despite multiple attempts, or when the user expresses frustration with lack of progress. Bring in GPT-5 as a third-party consultant to provide fresh perspective on complex technical problems, architectural decisions, or multi-system debugging issues. Ideal when you've tried multiple approaches without success, when the problem involves obscure edge cases or novel challenges, or when a second expert opinion would help break through an impasse. Gather all context from the conversation so far and present it comprehensively to GPT-5.

Create conference talk outlines and iA Presenter markdown slides using the Story Circle narrative framework. Use when the user wants to structure a tech talk, create presentation slides, or needs help organizing talk ideas into a story-driven format.

This skill should be used when the user asks to "test for XSS vulnerabilities", "perform cross-site scripting attacks", "identify HTML injection flaws", "exploit client-side injection vulnerabilities", "steal cookies via XSS", or "bypass content security policies". It provides comprehensive techniques for detecting, exploiting, and understanding XSS and HTML injection attack vectors in web applications.

This skill should be used when the user asks to "analyze network traffic with Wireshark", "capture packets for troubleshooting", "filter PCAP files", "follow TCP/UDP streams", "detect network anomalies", "investigate suspicious traffic", or "perform protocol analysis". It provides comprehensive techniques for network packet capture, filtering, and analysis using Wireshark.

This skill should be used when the user asks to "test for broken authentication vulnerabilities", "assess session management security", "perform credential stuffing tests", "evaluate password policies", "test for session fixation", or "identify authentication bypass flaws". It provides comprehensive techniques for identifying authentication and session management weaknesses in web applications.

This skill should be used when the user asks to "deploy", "upload", "publish" a frontend project, static website, or build output. Also activates when user mentions "pinme", "IPFS deployment", or wants to host static files online.

Systematic workflow for debugging by reproducing bugs with real data, reducing test cases to minimal examples, and adding regression tests

Review code using Linus Torvalds' "good taste" philosophy. Eliminates defensive code, special cases, and deep nesting. Use when reviewing code quality, refactoring, or checking for code smells.

Validate iPlug2 plugin builds using format-specific validators (auval, pluginval, vstvalidator, clap-validator) (project)

Download iPlug2 dependencies including plugin format SDKs (VST3, CLAP, WAM) and optional Skia graphics backend libraries

Guide to the AsyncDrop pattern for async cleanup in Rust. Use when working with AsyncDropGuard, implementing AsyncDrop trait, or handling async resource cleanup.

Upgrade simple-icons to the latest version and preserve any removed icons by sourcing them from the previous version into common/icons/customIcons.ts and updating icon mappings. Use whenever bumping or upgrading simple-icons in this repo.

This skill should be used when managing the file-based todo tracking system in the todos/ directory. It provides workflows for creating todos, managing status and dependencies, conducting triage, and integrating with slash commands and code review processes.